体重指数增加的异性恋易发生不育

美国国立健康医学分析方法所顺利进行的一项分析方法推测，与但会增重的成年来得，增重指标降低的成年后代可能性巨大。

Markku Sallmen就职于丹麦职业卫生分析方法所。他问道：“数据库看出，成年增重每降低20磅（约9公斤），后代的可能性将降低10%。”增重指标是由人的增重和身材高大计算得来的数据库，对大多数人，增重指标可视为身体心血管疾病的可靠指标，也常被用来肾结石增重较重。

学术界对工商业卫生分析方法构想中会特许的女儿顺利进行了分析方法。这项早于1993年的构想意在是为了检测因素工商业社区农民及其父母健康的因素所。

国立健康医学分析方法所的流行病学家Donna Baird博士问道：“与增重但会的娼妓来得，较重或心血管疾病的娼妓非常容易生孩子，但是同样情况的成年是否存在生育情况尚从未有人分析方法。”这项结果发表在2006年9月《流行病学新闻周刊》上。

后代和增重指标的数据库资料取自1468位农民和他们的妻子在登记纳入这项分析方法时完成的测试者。后者完成父母健康调查表，都有女儿的生育史，前者报告父母增重和身材高大的调查表。分析方法分析方法限于登记特许4年前想生育及长辈年纪低于40的女儿。

学术界将这些女儿分成后代组和可育组，高达1年从未不孕者归为后代组，在1年内不孕者归为可孕组。大多数成年和男士年纪高达30岁，28%的女儿有后代症状。

学术界推测成年的增重指标是后代症的独立可怕因素所。分析方法员更改了其它因素生育力的因素所，如男士的高增重指标、年纪、酒精、饮、暴露于药剂，更改过后，随着增重指标的降低，后代黄绿色频域降低，在心血管疾病成年，后代率降低1倍。学术界还推测无论年纪尺寸，成年的增重指标都是后代症的可怕因素所。

虽然没有频率的数据库，但据推测较重的成年较增重但会的成年数目少，从而因素了生育。然而，关于精子特性的分析方法推测较重和心血管疾病的成年，精子质量较低，激素不平衡。

国立健康医学分析方法所的主任Did A. Schwartz博士问道：“这项分析方法提出了某些与心血管疾病有关的另外的健康情况，抑制心血管疾病可促进成年健康，其中会就都有他们的卵巢健康。”该分析方法所还提出了一项新的战略目标的构想——“环境医学和生命体健康的新中间地带”，这项构想将于来年5月实施，意在在于利用健康医学促进公众了解疾病的发病原因并促进生命体健康。

Men with increased body mass index (BMI) were significantly more likely to be infertile than normal-weight men, according to research conducted at the National Institute of Environmental Health Sciences (NIEHS), one of the National Institutes of Health."The data suggest that a 20-pound increase in men's weight may increase the chance of infertility by about 10 percent," says Markku Sallmen, lead author on the paper who is now at the Finnish Institute of Occupational Health. BMI is a number calculated from a person's weight and height. BMI provides a reliable indicator of body fatness for most people and is used to screen for weight categories that may lead to health problems.The researchers studied couples enrolled in the Agricultural Health Study (AHS), a large project that began in 1993 examining factors that impact the health of farmers and their families in agricultural communities. "Women who are overweight or obese tend to he a more difficult time becoming pregnant than normal-weight women, but whether men who are overweight or obese also he fertility problems had not been studied," says Donna Baird, Ph.D., an NIEHS epidemiologist with the study. The study is published in the September 2006 issue of Epidemiology.The data on infertility and body mass came from questionnaires that 1,468 farmers and their wives completed when they enrolled in the study. The wives completed a family health questionnaire, which included information about the couple's reproductive history. The men reported their weight and height on a questionnaire about their health. The ysis was limited to couples with a pregnancy attempt during the four years before enrollment, and to women under the age of 40. The researchers divided the couples into infertile and fertile groups. The infertile couples were those that tried for longer than a year to conceive, and the fertile couples were those that conceived within a year. The majority of men and women were more than 30 years old. Twenty-eight percent of the couples had experienced infertility.Researchers found that men's BMI was an independent risk factor for infertility. The researchers adjusted for other factors that could affect fertility, including high BMI of the woman, age, cigarette smoking, alcohol intake, and solvent and pesticide exposure. After adjustment, there was a general increase in infertility with increased BMI, reaching a nearly 2-fold increase among obese men. When researchers divided the sample into two equal groups by men's age, they found that men's BMI was a risk factor for infertility in both the older and younger men.The researchers did not he data on frequency of sexual intercourse, so it is possible that overweight men he less sexual intercourse than their normal weight counterparts and this could influence fertility. However, there he been recent studies looking at semen characteristics that show lower semen quality for overweight and obese men, as well as hormonal differences."This study provides data on some additional health problems associated with obesity," said Did A. Schwartz, M.D., director of the National Institute of Environmental Health Sciences. "Preventing obesity can help improve men's overall health, perhaps even their reproductive health."The NIEHS unveiled a new strategic plan, "New Frontiers in Environmental Sciences and Human Health," in May aimed at challenging and energizing the scientific community to use environmental health sciences to understand the causes of disease and to improve human health.取自

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编辑： 张靖